田中 完 (たなか ひろし)

 

生年月日 195810

 

略歴:  1985年 弘前大学医学部卒業

              1989年 弘前大学大学院医学研究科修了

              1995年 弘前大学医学部附属病院周産母子センター助手

              1999年 弘前大学医学部附属病院小児科助手

              2001年 弘前大学医学部附属病院小児科講師

              2010年 弘前大学教育学部教授

 

学位:  医学博士 (1989年、弘前大学)

専門:  小児科学、小児腎臓病学、小児リウマチ学、小児アレルギー学

資格:  医師免許 (1985)、日本小児科学会専門医 (1991)、日本腎臓学会認定専門医 (1997)、日本腎臓学会認定指導医 (2003)、日本医師会認定産業医 (2010)

その他:日本腎臓学会学術評議員、日本小児腎臓病学会評議員、日本小児腎臓病学会雑誌編集委員、Editorial Board of Journal of Nephrology and Renal Transplantation, Editorial Board of Open Autoimmunity Journal、東北小児腎臓病研究会世話人、東北小児喘息アレルギー研究会幹事、青森県小児科医会顧問

 

所属学会:日本小児科学会、日本腎臓学会、日本アレルギー学会、日本小児腎臓病学会、日本小児アレルギー学会、日本小児リウマチ学会、米国腎臓学会、国際小児腎臓学会

 

研究:小児腎疾患・リウマチ性疾患の病態解明、より非侵襲的な治療法の開発、尿沈渣細胞を用いた腎疾患の非侵襲的な診断法の開発、培養メサンギウム細胞を用いた腎疾患における炎症過程の解明など.

 

主要論文:

1.    Imaizumi T, Tanaka H, et al. Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand (CCL) 5 in human mesangial cells. Nephrol Dial Transplant 2010; DOI: 10.1093/ndt/gfq2.

2.      Imaizumi T, Tanaka H, et al. Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-γ in human mesangial cells in culture: possible involvement of RIG-I in the inflammation in lupus nephritis. Lupus 2010; DOI: 10.1177/09612603309360540.

3.      Tanaka H, et al. Management of young patients with lupus nephritis using tacrolimus administered as a single daily dose. Clin Nephrol 2009; 72: 430-436.

4.      Tanaka H, et al. Mizoribine treatment of young patients with severe lupus nephritis: A clinicopathologic study by the Tohoku Pediatric Study Group. Nephron Clin Pract 2008; 110: c73-c79.

5.      Tsugawa K, Tanaka H, et al. Expression of mRNA for functional molecules in urinary sediment in glomerulonephritis. Pediatr Nephrol 2008; 23: 395-401.

6.      Fuchizawa T, Tanaka H, et al. Developmental changes of FOXP3-experssing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations. Clin Immunol 2007; 125: 237-246.

7.    Tanaka H, et al. Effective treatment of young patients with pediatric-onset, long-standing lupus nephritis with tacrolimus given as a single daily dose: An open-label pilot study. Lupus 2007; 16: 896-900.

8.      Tanaka H, et al. Treatment of difficult cases of systemic-onset juvenile idiopathic arthritis with tacrolimus. Eur J Pediatr 2007; 166: 1053-1055.

9.      Tanaka H, et al. Long-term mizoribine intermittent pulse therapy for young patients with flare of lupus nephritis. Pediatr Nephrol 2006; 21: 962-966.

10.  Tanaka H, et al. Renal biopsy findings in children receiving long-term treatment with cyclosporine A given as a single daily dose. Tohoku J Exp Med 2006; 209: 191-196.

11.  Nakahata T, Tanaka H, et al. C1-C2 point monitoring of low-dose cyclosporin A given as a single daily dose in children with steroid-dependent relapsing nephrotic syndrome. Clin Nephrol 2005; 64: 258-263.

12.  Tanaka H, et al. Low-dose cyclosporine A in a patient with X-linked immune dysregulation, polyendocrinopathy and enteropathy. Eur J Pediatr 2005; 164: 779-780.

13.  Tanaka H, et al. Single-dose-daily administration of cyclosporin A for relapsing nephrotic syndrome. Pediatr Nephrol 2004; 19: 1055-1058.

14.  Tanaka H, et al. Combined therapy of enalapril and losartan attenuates histologic progression in immunoglobulin A nephropathy. Pediatr Int 2004; 46: 576-579.

15.  Tanaka H, et al. Mizoribine oral pulse therapy for patients with disease flare of lupus nephritis. Clin Nephrol 2003; 60: 390-394.